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The High Guide Podcast: Microdosing for Midlife — Week 4: Stability, Change, and the Nervous System


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121. Microdosing for Midlife: Stability & Nervous System Change (Week 4)

Week 4 of Microdosing for Midlife explores how nervous system stability shapes identity, growth, and long-term change in midlife.

Episode Summary

This episode is part Week 4 of Microdosing for Midlife—a 12-part audio companion to the original Substack series.

In this conversation, April expands on what it actually means to feel stable while undergoing change. Midlife often brings visible transitions—shifts in hormones, identity, relationships, ambition—but underneath those external markers is something quieter: the nervous system recalibrating itself. Rather than focusing on dramatic breakthroughs, this episode examines how safety, steadiness, and subtle internal shifts create sustainable growth.

Instead of chasing intensity, April reflects on how microdosing can support capacity—capacity to tolerate discomfort, to remain present in uncertainty, and to integrate insight gradually. The real work is not in peak moments. It’s in the ability to return to baseline without abandoning yourself.

🔵 Key Takeaways

How nervous system stability shapes long-term growth in midlife

Why intensity is often mistaken for progress

How subtle shifts accumulate into meaningful identity change

What “capacity building” looks like beyond insight

A reflection question to carry into the week ahead

🔵 Timestamps

[00:00] Episode opening[02:00] Framing the week’s theme[08:30] Nervous system stability vs intensity[15:00] Capacity building in midlife[22:00] Integration reflection[27:00] What to carry forward

🔵 Resources

Micro-Psyched 12-Week Microdosing Program

Upcoming Psychedelic Salon tickets

Follow April on Substack

Original Microdosing for Midlife Substack post:https://aprilpride.substack.com/p/vagus-nerve-menopause-psilocybin-intuition-body-trust

Hosted by April Pride @aprilpride_

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Get full access to SetSet with April Pride at aprilpride.substack.com/subscribe

Catch the full episode here

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