The High Guide Podcast: Why & How to Start Microdosing: The Gentle Revolution

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114. How to Start Microdosing with Psilocybin

A science-backed guide to microdosing psychedelics with SetSet’s 12-week protocol, featuring expert insight and lived experience.

Episode Summary

If you’ve been microdose-curious — or maybe you’re already experimenting and want a little more structure — this episode is your map. Host April Pride pulls together insights from SetSet collaborators including author Amy Wong, integrative therapist Kendra Bloom, and medicine woman Sand Symes.

You’ll learn exactly what microdosing is, why it works, and how SetSet’s 12-week Micro-Psyched protocol guides real, sustainable shifts—especially for women navigating overwhelm, transitions, or burnout.

Whether you’re a total beginner or an experienced journeyer seeking structure, this episode will help you align mindset, medicine, and method.

Key Takeaways

Microdosing is a sub-perceptual, regular-dose protocol designed to shift your mental patterns gently over time.

There are three main microdosing personas: psychedelic curious, psychedelic conscious, and providers supporting others.

Microdosing supports subtle but profound behavior changes—like reducing compulsions or regaining clarity.

SetSet’s 12-week structure mirrors the natural cycle of change: preparation, resistance, and consolidation.

Real change doesn’t require fireworks. Tiny, steady choices reshape your reality.

Timestamps

00:36 What microdosing really is and how it works (Amy Wong)02:10 Three types of people who join SetSet’s protocol08:45 Why structure matters: stories from women in Micro-Psyched13:20 Real-life benefits from microdosing: cravings, clarity, choice18:00 Why 12 weeks? The brain’s timeline for transformation21:40 Live workshops: coming to Seattle in 202524:00 What’s included in SetSet’s Annual Membership27:10 Final reflections: microdosing as a relationship, not a hack

Guests

Amy Wong: Author of Living on Purpose | amywong.com

Kendra Bloom: Therapist, Integration Specialist | @kendrabloom

Sand Symes: Medicine woman and facilitator | @sandsymes

Additional Resources

Q: How Do Psychedelics Unlock Creativity?

Micro-Psyched 12-Week Microdosing Program

Women in the Wild application

Learn more about this episode: https://aprilpride.substack.com/p/how-to-start-microdosing-psilocybin

Hosted by April Pride

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